Oligonucleotide Chemist

Deep Genomics, Toronto, Ontario

Creating A New Universe Of Genetic Medicines

Duration: Full-Time

About Us
Deep Genomics is a Toronto-based startup company that is building an AI-powered discovery and development platform to significantly expand the universe of medicines available for genetically-defined diseases. Founded in 2015, Deep Genomics brings together a multidisciplinary team of world-leading experts in machine learning, genomics, chemistry, and biology. Together we are on a mission to rapidly discover and develop oligonucleotide drugs for the treatment of patients with severe disorders of the liver, central nervous system, and eye.

Ideal Candidate
We are seeking an ambitious and talented organic chemist to help us develop oligonucleotide therapies for rare diseases. This ideal candidate will lead the research and development of novel approaches to use oligonucleotides therapeutically and methods to characterize oligonucleotides and their effects in biological systems.  They will also work closely with our manufacturing partners to develop and optimize synthesis and characterization processes for oligonucleotides and associated ligands.  They will support our clinical and regulatory teams in complying with regulatory requirements and documentation. They will have a flexible attitude to job roles and superlative organizational, interpersonal, and communication skills.


  • PhD in Chemistry, Biochemistry or related discipline
  • Extensive experience in oligonucleotide synthesis, characterization and/or manufacturing
  • Previous experience in working with CROs and CMOs for process development and manufacturing of oligonucleotides is highly desirable, preferably in a regulated environment (i.e. GMP)

What we offer:

  • A highly competitive salary, health and dental benefits, and meaningful equity compensation.
  • Exceptional opportunities for learning and growth.
  • A collegial working environment with regular social events for team members and their families.
  • You’ll also be joining a bright and highly-motivated team working at the intersection of the most exciting areas of science and technology.
Deep Genomics thanks all applicants, however only those selected for an interview will be contacted. 

Deep Genomics welcomes and encourages applications from people with disabilities.
Accommodations are available on request for candidates taking part in all aspects of the selection process.

About Deep Genomics

Deep Genomics is using artificial intelligence to build a new universe of life-saving genetic therapies. The future of medicine will rely on artificial intelligence, because biology is too complex for humans to understand. At Deep Genomics, our geneticists, molecular biologists and chemists develop new ways of detecting and treating disease using our biologically accurate artificial intelligence technology.

Deep Genomics

Want to learn more about Deep Genomics? Visit Deep Genomics's website.