Uncubed
           

Senior Scientist - Assay Development

Ginkgo Bioworks, Boston, MA

THE ORGANISM COMPANY


Our mission is to make biology easier to engineer.  Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more.  Our bioengineers make use of an in-house automated foundry for designing and building new organisms.  Today, our foundry is developing over 40 different organisms to make different products across multiple industries.

Core to our organism engineering pipeline is the testing and analysis of our engineered strains. We leverage high throughput screens and selections to measure thousands of strains at a time for improved enzyme activity of key steps or increased titers of final products. Given the diversity of projects at Ginkgo, your assay development approaches need to work across multiple hosts and products of interest. If successful, your new screening and selection methods will lie at the center of our new high throughput screening pipelines.

The ideal candidate has led the development of enzymatic activity screens, microbial phenotypic screens, or genetic selections from conception, development, and piloting through execution. Experience with screens or selections based on NGS, biosensors, or clever genetic selections are of interest.

Responsibilities

  • Develop and validate new high throughput screens and selections for products of interest
  • Apply DOE methods to reduce assay CV and increase reproducibility
  • Scale assays to work on >10,000 strains per week via software + automation
  • Analyze large-scale experimental datasets and communicate screening results effectively with product teams and customers as necessary
  • Collaborate with software engineers to ensure that all data is captured, stored, and analyzed in Ginkgo's LIMS

Requirements

  • PhD in biology, biochemistry, bioengineering, chemistry, chemical engineering or equivalent with 3+ years industry experience
  • Demonstrated ability to develop novel assays and optimize conditions to reduce variability
  • Enzymology experience a plus
  • Familiarity with software, programming, or laboratory automation a plus
  • Familiarity with diverse microbes, including plant-associated microbes, a plus
To learn more about Ginkgo, check out some recent press:

We also feel it’s important to point out the obvious here – there’s a serious lack of diversity in our industry and it needs to change.  Our goal is to help drive that change.  We hope to continue to build a company whose culture promotes inclusion and embraces how rewarding it is to work with engineers from all walks of life.  Making biology easier to engineer is a tough nut to crack –  we can’t afford to leave any talent untapped.  

It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees and employment applicants.

About Ginkgo Bioworks

Ginkgo Bioworks is the organism company. We design custom microbes for customers across multiple markets. We build our foundries to scale the process of organism engineering using software and hardware automation. Organism engineers at Ginkgo learn from nature to develop new organisms that replace technology with biology.

Want to learn more about Ginkgo Bioworks? Visit Ginkgo Bioworks's website.